2005-2006 Pocket Book of Infectious Disease Therapy by John G. Bartlett MD

By John G. Bartlett MD

Designed to supply easy access to criteria of deal with infectious sickness via targeting choice, right doses, charges, and unintended effects of antimicrobial brokers, the 2005-2006 notebook of Infectious illness Therapy attracts greatly from options made by means of the facilities for disorder regulate and Prevention, the scientific Letter on medicinal drugs and Therapeutics, and from respectable statements of revered scientific societies. Tabular fabric has been up-to-date to incorporate all newly authorized antibiotics, in addition to new thoughts for management.

This version comprises topical concerns equivalent to MRSA (USA three hundred strain), Avian influenza, Acinetobacter Hepatitis B virus (HBV), hepatitis C virus (HCV), and bioterrorism. It additionally comprises the hot directions for pyogenic meningitis, diabetic foot infections, healthcare linked pneumonia, surgical prophylaxis, fungal infections, bacteruria, and administration of infections linked to foreign travel.

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Extra resources for 2005-2006 Pocket Book of Infectious Disease Therapy

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C. Obese patients: Use lean body weight. d. Renal failure: Formulas assume stable renal function; for patients with anuria or oliguria assume creatine clearance (CCr) of 5-8 mL/min. B. AMINOGLYCOSIDE DOSING 1. 12 × CCr = mg/kg/8 h 20-40 μg/mL Doses for gentamicin and tobramycin should be written in multiples of 5 mg; doses of amikacin and kanamycin should be written in multiples of 25 mg. , 3 mg/kg for gentamicin and tobramycin. b c Obese patients: use calculated lean body weight plus 40% of excess fat.

4 ? 400 mg /d — Usu al 200 mg/d 100 mg /d Ceftizoxime Renal 1. 41. 5 g q24 h Ceftriaxone Renal and biliary 69 1215 — 1-2 g q24h Usu al Usual Usu al Cefuroxime Renal 1. 31. 7 5g q24 h Cefuroxime axetil Renal 1. 2 20 250 mg q12 h — Usu al Usual 250 mg q24 h Cephalexin Renal 0. 2 5-1 g q24 48h Cephalothin Renal 0. 50. 5 g q8h Cephapirin Renal 0. 60. 52g q12 h Cephradine Renal 0. 51g q24 72h Chlorampheni col Hepatic 2. 25 -1 g q6h Usu al Usual Usu al Chloroquine Renal and metaboliz ed 48 12 0 ? 300 600 mg po qd — Usu al Usual 150 300 mg po qd Cidofovir Renal 17 65 ↑ — 5 mg/ kg q 2 wk Usu al Contraindica ted Cinoxacin Renal 1.

Aureus (NEJM 2003;348:1342; MMWR 2002;51:565) As above Linezolid; daptomycin (except pneumonia) Quinupristin-dalfopristin; some strains sensitive to tetracycline, TMP-SMX, chloramphenicol Urinary tract infections Sulfa-trimethoprim Ampicillin/amoxicillin Fluoroquinolone (6) Cephalosporins (5); tetracycline (4); tigecycline Methicillin-sensitive Septicemia Infected prosthetic devices Oxacillin/nafcillin Cephalosporin (1st gen) (5) Beta-lactam-BLI (7); fluoroquinolone (6); imipenem/meropenem/ertapenem; vancomycin; tigecycline Methicillin-resistant Septicemia Infected prosthetic devices Vancomycin ± gentamicin or rifampin Daptomycin; linezolid; (possibly effective— chloramphenicol, rifampin, tetracycline); tigecycline Stenotrophomonas maltophilia (Xanthomonas maltophilia) Septicemia, pneumonia, UTI Sulfa-trimethoprim; tigecycline Ceftazidime; fluoroquinolone (6); minocycline Streptobacillus moniliformis Rat-bite fever Haverhill fever Penicillin G IV × 5-7 d, then amoxicillin × 7d Tetracycline (4); erythromycin; clindamycin; streptomycin Streptococcus, groups B, C, G; S.

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